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16th Annual Surgical Resident and Fellow Research Presentation Day

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2009 Program
We were pleased to welcome Dr. Blake Cady as our visiting professor and judge. Drs. Desmond Birkett, Patricia Donahoe, and Steven Schwaitzberg joined him as judges. This year there were many more submissions than could be presented today demonstrating the continued enthusiasm for surgical research here in New England.
9:00 – 9:20 AM Introduction and Welcome
9:20 AM  Sternal Repair with Bone Engineered from Amniotic Mesenchymal Stem Cells in an Allogeneic Leporine Model
Justin D. Klein; Christopher G.B. Turner; Shaun A. Steigman; Azra Ahmed; Dario O. Fauza
Children’s Hospital Boston – Surgery, Boston, MA
9:30 AM Novel Ambulatory Lung Assist Device Oxygenates and Removes Carbon Dioxide from Blood Across a Silicone-Coated Porous Membrane
David M. Hoganson, MD,1 Jennifer L. Anderson, MD,1 Eli F. Weinberg, PhD,2 Eric J. Swart, BS,2 James C. Hsiao BS,2 Brian K. Orrick, BS,2 Jeffrey T. Borenstein, PhDb Joseph P. Vacanti, MDa
1Center for Regenerative Medicine, Department of Surgery, Massachusetts General Hospital, Boston, MA 2Charles Stark Draper Laboratory, 555 Technology Square, Cambridge, MA
9:40 AM  Endothelial Cells with Eph B4 Heterozygous Knockdown: A Novel Cellular Model of Vein Graft Adaptation
Amanda Feigel MD, Akihito Muto MD, PhD , Mariangela Rivera, Aaron Feinstein, Susun Kim, Yuka Kondo MD, PhD, Alan Dardik MD, PhD
Yale University School of Medicine, New Haven, CT
9:50 AM The role of VAV guanine nucleotide exchange factor in Dectin-1 mediated phagocytosis.
Jill K. Johnstone, MD, Nicole A. Morin, B.S., William G. Cioffi, MD, Jonathan S. Reichner, PhD.
Department of Surgical Research, Rhode Island Hospital, Warren Alpert Medical School, Brown University, Providence, RI.
10:00 AM  Intestinal alkaline phosphatase downregulates TLR-mediated Il-8 induction by dephosphorylation of cognate ligands
Kathryn Chen MD, Madhu Malo MD, Skye Zeller, Paul Johnson, Golam Mostafa MD, Sayeda Alam MD, Sunny Ramasamy PhD, Elizabeth Hohmann MD, Richard Hodin MD
Massachusetts General Hospital, Boston, MA
10:10 AM N-acetyl-L-cysteine (NAC) reduces intraabdominal adhesion formation through the upregulation of peritoneal fibrinolytic activity and antioxidant defenses
Daniel Chu MD, Rizal Lim MD, Stanley Heydrick PhD, Karen L. Reed PhD, Arthur F. Stucchi PhD, and James M. Becker MD FACS
Boston University Medical Center, Dept of Surgery, Boston, MA
10:10 – 10:40 AM Break
10:40 AM YKL-40 A Potential Biomarker for Colorectal Cancer
Hannah K. Swayze, MD, Christopher N. Chapman, MD, Jackie Cao, MD, Rong Shao, PhD, Brooke Bentley, Richard B. Arenas, MD
Baystate Medical Center/Tufts University School of Medicine, Springfield, MA
10:50 AM  Measuring Surgical Site Infections as a Quality Improvement Project. Comparing Patient Survey with Surgeon Survey and Chart Review.
Dawn M Stapleton, MD, Robert Hawkins, MD, Douglas Salvador, MD
Maine Medical Center, Dept of Surgery, Portland, ME
11:00 AM The Value Of Intraoperative Frozen Section Examination In Sentinel Lymph Node Biopsy For Breast Cancer
Shonan Shetly, MD, Jose M. Pimiento, MD, Michael S. Ajemian, MD
Saint Mary's Hospital, Surgery, Waterbury, CT
11:10 AM Oncotype-Dx Assay in a community hospital cancer center. Is the additional cost justified?
Manny G. Trujillo, MD, Kerry L. Wheeler, DO, R. Barry Hird, MD, Richard K. Orr, MD MPH
Spartanburg Regional Medical Center, Dept. of Surgery, Spartanburg, SC
11:20 AM  Modified Clinical Scoring System Decreases Use of CT scan in Diagnosis of Pediatric Acute Appendicitis
Hussain M.A. Abbas, MD, Amy Rezak, MD, Michael Ajemian, MD FACS
Saint Mary's Hospital - Yale Affiliate, Waterbury, CT
11:20 AM Modified Clinical Scoring System Decreases Use of CT scan in Diagnosis of Pediatric Acute Appendicitis
11:30 AM Combating Fatigue in Surgical Residency Programs
Frank Mccormick, MD
Harvard Orthopedic Surgery, Cambridge, MA
11:40 AM  A move to the right? the viability of alternatives to colonoscopy
Sun MY, Pugsley SL, Simons JP, Tseng Jf, Maykel JA, Sweeney WB, Alavi K
Universtity of Massachusetts, Surgery, Worcester, MA
11:50 AM  Adherence to VAP Bundle Decreases Incidence of Ventilator-Associated Pneumonia in the Trauma Intensive Care Unit
Dorothy W. Bird MD, Charlie O’Donnell, Julie Silva, Cathy Korn MPH, Robert Burke, Peter Burke MD, and Suresh Agarwal MD
Boston Medical Center/ Department of Surgery, Boston, MA
12:00 – 1:00 PM Lunch
1:00 PM Suppressive Regulatory T cell Activity is Potentiated by Glycogen Synthase Kinase 3 Inhibition
Jay Graham, MD1, Michael Fray1, Stephanie de Haseth1, Catharine M. Chase1, Robert B. Colvin, MD2, Joren C. Madsen, MD, D.Phil.1, A. Benedict Cosimi, MD1, Gilles Benichou, Ph.D.1, and Alessandro Alessandrini, Ph.D.1.
1Department of Surgery, Transplantation Unit, 2Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA
1:10 PM Neural Stem Cell Delivery to the Spinal Cord in an Ovine Model of Fetal Surgery for Spina Bifida
Christopher G.B. Turner; Justin D. Klein; Russell W. Jennings; Evan Y. Snyder; Dario O. Fauza
Children’s Hospital Boston, Boston, MA
1:20 PM Colectomy For Colonic Polyps In The Era Of Minimally Invasive Surgery: Are We Following Oncologic Principles?
Mandip Joshi, Jose M. Pimiento, M Joshi, J Hawkes, SJ Dudrick, M Ajemian
Saint Mary's Health System, Waterbury, CT
1:30 PM  Radical resection for T1b gallbladder cancer: a decision analysis
Michael A. Abramson1,4, Pari Pandharipande,3,4, Daniel Ruan1,4, Jason S. Gold1,4, & Edward E. Whang1,4
1Department of Surgery, Brigham & Women’s Hospital 2Department of Radiology, Massachusetts General Hospital 3Institute for Technology Assessment, Massachusetts General Hospital 4Harvard Medical School, Boston, Massachusetts
1:40 – 2:30 PM Consider Being Contrarian Not Transfixed by Technology
Keynote Speaker:
Blake Cady, MD
2:30 PM Amniotic Mesenchymal Stem Cells Play a Role in Fetal Wound Healing
Justin D. Klein; Shaun A. Steigman; Christopher G.B. Turner; Azra Ahmed; Dario O. Fauza
Children’s Hospital Boston – Surgery, Boston, MA
2:40 PM Pathophysiologic characterization of tissue engineered vascular graft stenosis in a murine model
Gustavo Adolfo Villalona MD, Narutoshi Hibino MD, PhD, Edward McGillicuddy MD, Rajendra Sawh-Martinez, Tamar Mirensky MD, Toshiharu Shinoka MD, PhD, Christopher Kane Breuer MD
Yale University School of Medicine, New Haven, CT
2:50 PM  Pterostilbene Inhibits Lung Cancer through Induction of Apoptosis
John G. Schneider MD, Julie A. Alosi, MD, David W. McFadden, MD
University of Vermont, Burlington, VT
3:00 PM  Prenatal Tracheal Repair with Cartilage Engineered from Amniotic Mesenchymal Stem Cells in an Allogeneic Ovine Model
Shaun M. Kunisaki; Christopher G.B. Turner; Justin D. Klein; Deborah Freedman; Dario O. Fauza
Children's Hospital Boston, Boston, MA
3:15 PM Awards and Ice Cream Social!

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