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17th Annual Surgical Resident and Fellow Research Presentation Day

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New England Surgical Society’s
17th Annual
Surgical Resident and Fellow
Research Presentation Day Program
9:00 AM Introduction and Welcome
9:10 AM Histopathologic Responses to Synthetic Meshes In a Mouse Model
Sean B. Orenstein, MD1, Ean R. Saberski, BS2, Donald L. Kreutzer, PhD3, Yuri W. Novitsky, MD1
1Connecticut Comprehensive Center for Hernia Repair, Department of Surgery, University of Connecticut Health Center, Farmington, Connecticut, USA 2University of Connecticut School of Medicine, Farmington, Connecticut, USA 3Center for Molecular Tissue Engineering, Department of Surgery, University of Connecticut School of Medicine, Farmington, Connecticut, USA
9:20 AM Late Adhesiolysis For Adhesive Small Bowel Obstruction (ASBO) Is Safe But Increases Post-Operative Length of Stay and In-hospital Cost Compared To Early Adhesiolysis: Nationwide Analysis of Inpatient Outcomes.
Daniel I. Chu MD, Jeremy T. Hetzel MPH, Melanie L. Gainsbury MD, Lauren A. Howard MPH, Arthur F. Stucchi PhD, and James M. Becker MD FACS
Department of Surgery, Boston University Medical Center, Boston, MA
9:30 AM A Half Century of Burn Epidemiology and Burn Care in a Rural State
Lee D. Hallagan MD, Laura L. Blaisdell MD/MPH, Reeve Chace MPH, David E. Clark MD/MPH
Maine Medical Center, Portland, ME
9:40 AM The Management of Pancreatic Injuries in Children: Operate or Observe
Michael D. Paul, MD, David Mooney, MD, MPH
Children’s Hospital Boston, Boston, MA
9:50 AM  Pre-Clinical Regulatory Validation of a 3-Stage Amniotic Mesenchymal Stem Cell Manufacturing Protocol
Christopher G Turner, Justin D Klein, Myriam Armant, Lucy Bayer, Jerome Ritz, Dario O Fauza
Children's Hospital Boston, Department of Surgery, Boston, MA
10:00 AM  Local Peritoneal Irrigation with Intestinal Alkaline Phosphatase Is Protective against Peritonitis in Mice
Farzad Ebrahimi1, MD, Madhu S. Malo1, MD, Sayeda Nasrin Alam1, MD, Sundaram Ramasamy1, PhD, Angela K. Moss1, MD, Kathryn T. Chen1, MD, Brishti Biswas1, BS, Halim Yammine1, MD, Shaw H. Warren2, MD, Elizabeth L. Hohmann3, MD and Richard A. Hodin, MD1
1Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 2 Infectious Disease Unit, Department of Pediatric and Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 3 Infectious Disease Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston MA
10:10 – 10:30 AM Break
10:30 AM Müllerian Inhibiting Substance: preparation for the clinic
Meirelles, K*; Papakostas TD**; Chang, MD*; Vavvas, D**, Maclaughlin, DT*; Donahoe, PK*
* Pediatric Surgery Laboratories – MGH ** Department of Ophthalmology, Massachusetts Eye and Ear Infirmary
10:40 AM Pterostilbene Promotes Interferon Alpha 2b Effects on Melanoma In Vitro
Patrick Mannal, MD; Debbie McDonald, BS; David McFadden, MD, MBA, FACS
University of Vermont, Burlington, VT
10:50 AM Indications For Preoperative Retrievable Inferior Vena Cava Filters For Bariatric Patients Must Be Reevaluated
Robert A. Brenes, MD, Laila Rashidi, BA, Hussain M. A. Abbas, MD, J. Alexander Palesty, MD, FACS
St. Mary’s Hospital, Stanley J. Dudrick Department of Surgery, Waterbury, CT
11:00 AM Treatment of massive, irreparable rotator cuff tears with transfer of the latissimus dorsi muscle. A multidisciplinary approach
Aleksandra Krajewski, Jeffrey Wu, Mark Cote, Augustus Mazzocca, Rajiv Chandawarkar
University of Connecticut Health Center, Farmington, CT
11:10 AM Elastic Scattering Spectroscopy (ESS) for Discrimination of Benign from Malignant Disease in Thyroid Nodules
Hyunsuk Suh, M.D.1, Samuel Kim B.A.1, Susannah Orzell B.A.1, Ousama A’amar Ph.D. 3,Eladio Rodriguez Ph.D. 3, Stephanie L. Lee, M.D., PhD. 2, Irving Bigio, Ph.D. 3, Jennifer E. Rosen, M.D., F.A.C.S. 1
1Department of Surgery, 2Department of Medicine, Section of Endocrinology, Diabetes and Metabolism and 3Department of Biomedical Engineering, Boston University, Boston, Massachusetts
11:20 AM Varying Clinical and Radiological Presentations of Duodenal Gastrointestinal Stromal Tumors
K. L. Jackson , D.J. Grand, M. B. Resnick, K. P. Charpent
Brown University, Rhode Island Hospital, Surgery, Providence, RI
11:30 AM Endothelial-derived epoxyeicosatrienoic acids promote organ regeneration
Hau D Le1,2, Mark W Kieran1,7, Darryl C Zeldin3, Brian Kalish1,2, Vincent E de Meijer1,2, Matthew L Edin3, Craig R Lee4, Jo-Anne Vergilio5, Bruce D Hammock6, Mark Puder1,2, Dipak Panigrahy1,7
1Vascular Biology Program, Children's Hospital, Harvard Medical School, Boston, MA. 2Department of Surgery, Children’s Hospital, Harvard Medical School, Boston, MA 3Laboratory of Respiratory Biology, National Institute of Environmental Health Science, National Institute of Health, Research Triangle Park, NC. 4Division of Pharmacotherapy and Experimental Therapeutics, School of Pharmacy, University of North Carolina, Chapel Hill, NC 5Department of Pathology, Brigham and Women's Hospital, Boston, MA, Boston, MA. 6Department of Entomology and Cancer Research Center, University of California, CA. 7Division of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA.
11:40 AM Intestinal alkaline phosphatase detoxifies the bacterial ligand flagellin
Angela K Moss MD, Madhu Malo MD, Kathryn Chen MD, Sundaram Ramasamy PhD, Sayeda Alam MD, H. Shaw Warren, Elizabeth Hohmann MD, Richard Hodin MD
Massachusetts General Hospital, Surgery, Boston, MA
11:50 – 12:50 PM Lunch
12:50 PM Unique effects of cardiopulmonary bypass on gene expression profiles in skeletal muscle and blood
Louis M Chu, MD1 , Basel Ramlawi, MD2, Cesario Bianchi, MD, PhD1, Frank W Sellke, MD1
1Alpert Medical School of Brown University, Providence, RI 2Methodist DeBakey Heart and Vascular Center, Houston, TX
1:00 PM Hand Hygiene and Hospital-Acquired Infection in the Surgical Intensive Care Unit
Dorothy Bird, MD, Dale Ford, Carol Sulis, MD, Peter Burke, MD, Suresh Agarwal, MD
Boston University Medical Center, Department of Surgery, Boston, MA
1:10 PM False positive CA 19-9: How high, how often, and clinical outcomes
Isaac W Howley Thomas J Miner, Kevin P Charpentier
Brown University, Surgery, Providence, RI
1:20 PM Death from Breast Cancer Occurs Predominantly in Women Not Participating in Mammographic Screening
Webb, Matthew1, Cady, Blake MD, FACS2
1Massachusetts General Hospital 2Cambridge Hospital
1:30 – 2:30 PM “Surgery Yesterday, Today, and Tomorrow”
Keynote Speaker: Edward Whang, MD
2:30 PM Cyclic Dynamic Strain of High Magnitude is Inflammatory in Rat Dermal Fibroblast
Holly K. Sheldon, MD, Peter Burke, MD, Suresh Agarwal, MD
Boston Medical Center, Department of Surgery, Boston, MA
2:40 PM Sulindac reverses aberrant expression and localization of
β-catenin in papillary thyroid cancer cells with the BRAFV600E mutation.

Nancy L. Cho, MD, Chi-Iou Lin, PhD, Edward E. Whang, MD, Adelaide M. Carothers, PhD, Francis D. Moore, Jr., MD, Daniel T. Ruan, MD
Department of Surgery, Brigham & Women's Hospital
2:50 PM Ventricular Restraint Therapy for Heart Failure: Is The Right Ventricle Different from the Left Ventricle?
Lawrence S. Lee, Ravi K. Ghanta, Suyog A. Mokashi, Otavio Coelho-Filho, Raymond Y. Kwong, Jan D. Schmitto, R. Morton Bolman III, Frederick Y. Chen
Division of Cardiac Surgery, Brigham and Women's Hospital, Boston, MA
3:00 PM Chronic Cyclooxygenase-2 Inhibition Promotes Intestinal Fibrosis in a Mouse Model of Colorectal Cancer
Davids, J.S., Carothers A.M., Bertagnolli, M.M.
Brigham and Women's Hospital and Harvard Medical School, Boston, MA
3:10 PM Surgical Vampires and Rising Healthcare Expenditure: the cost of daily phlebotomy
Elizabeth Stuebing MD, MPH, Thomas Miner MD
Alpert School of Medicine at Brown University
3:25 PM Awards

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